It depends on the nature of the business and the types of advantages or disadvantages of a particular location. In retail businesses there's an old saying: the three most important factors in your success are location, location and location. In manufacturing and services businesses, in an increasingly competitive world, a location where labor and resources are cheaper can make your products or services more competitive, as long as quality and reliability are adequate. In food and nutrition industries, locations that are pollution-free and pesticides-free will become increasingly important as sources of produce. In certain agricultural and manufacturing/processing industries, locations where water is plentiful and cheap are becoming more important.
